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Overview

The Duke University Macromolecular X-ray Crystallography Shared Resource offers services in determining and publishing macromolecular crystal structures. We offer everything from crystallization trials through data collection, structure phasing, refinement and analysis on a fee-for-service basis. Facility staff can assist with any and all steps in the process as needed. We are listed with the Duke Human Vaccine Institute's shared resources, the Duke University School of Medicine core research facilities, and the North Carolina Biotechnology Center's core laboratory facilities. We welcome inquiries from investigators associated with Duke as well as those associated with other research facilities throughout the state and beyond.

Getting Started

To best chart a course for new structural endeavors, we find it most helpful for investigators to discuss their intentions with us prior to any discussions regarding training, chemical safety, billing procedures and so forth. Contact us by phone, form or email (crystallography@duke.edu).

Coming soon! - UV Imaging Upgrade

We are proud to announce that our Minstrel HT crystal plate automated imager is being upgraded to the next generation Minstrel HT UV imager thanks to an awarded grant from the North Carolina Biotechnology Center through their Institutional Development Grant series. The Minstrel HT UV captures white light and UV light images for each crystal drop. Rigaku's new Fluor-Score software then analyzes the images to automatically produce a hit list of drops containing potential protein crystals for directed follow-up.